Growth hormone (GH) is arguably the most important anti-aging hormone. It is a long peptide molecule secreted by the pituitary gland consisting of 191 amino acids.

Many factors influence its production and release. The decline of growth hormone production and release is termed somatopause.

Some signs and symptoms of adult growth hormone deficiency or somatopause are increased body fat, reduced strength, depressed mood, anxiety, increased social isolation, thin skin, dry skin and poor muscular tone.